LL-37 10mg
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Description
LL-37 is a 37-amino-acid cationic peptide derived from the human cathelicidin precursor protein (hCAP-18). It exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi, while also modulating immune responses, promoting angiogenesis, and supporting wound healing in preclinical models.
Sequence & Composition
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Amino Acid Sequence:
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES -
Molecular Weight:Â ~4,493 Da
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Molecular Formula: C₂₀₅H₃₄₀N₆₀O₅₃
Research & Applications
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Antimicrobial Activity:Â Kills Gram-positive and Gram-negative pathogens, including antibiotic-resistant strains.
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Immunomodulation:Â Regulates cytokine production, inhibits excessive inflammation, and promotes dendritic cell maturation.
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Wound Healing:Â Enhances re-epithelialization and angiogenesis in skin injury models.
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Antiviral & Antifungal Effects:Â Blocks viral entry mechanisms and disrupts fungal membranes.
Recommended Usage
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In Vitro: 0.1–10 µM in cell culture or assay buffer.
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In Vivo (Rodent Studies): 1–5 mg/kg via subcutaneous or intravenous injection, once daily or per protocol.
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Solubility: Dissolve in sterile water or PBS; gentle warming (~37 °C) may aid dissolution.
Packaging & Storage
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Packaging:Â 10 mg amber glass vial with desiccant.
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Shelf Life:Â Up to 12 months unopened.
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Storage Conditions: Store at 2–8 °C; protect from light and moisture; avoid repeated freeze–thaw cycles.
For laboratory research use only. Not for human or veterinary consumption.
References
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Peptide Sciences: LL-37 5 mg (CAP-18) product page peptidesciences.com
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PubChem: LL-37 (CID 16198951)Â pubchem.ncbi.nlm.nih.gov
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InvivoGen: LL-37 overview invivogen.com







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