SKU: SQ2872621

SEMAX 10mg

$55.00

Semax

Description

Semax is a synthetic peptide analogue of the ACTH(4–10) fragment, renowned for its neuroprotective, nootropic, and immunomodulatory properties. It is widely used in preclinical and clinical research to:

  • Enhance cognitive function, memory retention, and learning

  • Promote neuronal survival and recovery in ischemic and traumatic brain injury models

  • Modulate gene expression involved in vasculogenesis and immune response

  • Exhibit antidepressant and anxiolytic-like effects

Its mechanism involves upregulation of brain-derived neurotrophic factor (BDNF), modulation of melanocortin receptors, and inhibition of enkephalinase activity.

Sequence & Composition

  • Amino Acid Sequence: H-Pro-Gly-Pro-Gly-Pro-Lys-Pro-Gly-Pro-OH

  • Molecular Formula: C₃₇H₅₁N₉O₁₀S

  • Molecular Weight: 850.9 Da

  • CAS Number: 80714-61-0

Research & Applications

  • Neuroprotection & Stroke Recovery: Accelerates functional recovery and supports angiogenesis in ischemic brain models pmc.ncbi.nlm.nih.gov

  • Cognitive Enhancement: Improves attention, memory performance, and stress resilience in both animal studies and human trials mdpi.com

  • Mood Regulation: Produces rapid antidepressant- and anxiolytic-like effects via BDNF/trkB modulation sciencedirect.com

  • Anti-Aggregating Activity: Inhibits amyloid-β fibril formation and provides protective effects against oxidative stress pubs.acs.org

Recommended Usage

  • In Vitro: 0.1–10 µM in cell culture assays

  • In Vivo (Rodent Studies): 250–1,000 µg/kg via intranasal, subcutaneous, or intravenous administration, per protocol

  • Handling: Reconstitute in sterile water or PBS; avoid repeated freeze–thaw cycles

Packaging & Storage

  • Packaging: 10 mg amber glass vial with desiccant pack

  • Shelf Life: Up to 12 months unopened

  • Storage Conditions: Store at 2–8 °C; protect from light and moisture

For laboratory and research use only. Not for human or veterinary consumption.

References

  1. Ushakova et al., “Semax influences gene expression during focal ischemia,” PLoS One (2014) pmc.ncbi.nlm.nih.gov

  2. ACS Chemical Neuroscience, “Semax anti-aggregating properties” (2019) pubs.acs.org

  3. ScienceDirect, “Semax modulates BDNF/trkB system” (2006) sciencedirect.com

  4. Particle Peptides product overview: “Semax as a cognitive enhancer” particlepeptides.com

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FAQ

Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.

Yes. Reverse Peptides offers 99% purity, third-party tested, and USA-made peptides. Our products are backed by quality assurance and a loyal base of researchers

Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.

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No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.