Acetylhexapeptide 10mg

$35.00

Acetylhexapeptide 10mg

Description

Acetyl Hexapeptide-8 (often marketed as Argireline®) is a synthetic hexapeptide (sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂) designed to mimic a fragment of SNAP-25 and modulate neurotransmitter release. By competing for SNARE-complex binding, it can help inhibit muscle micro-contractions—resulting in reduced appearance of dynamic wrinkles and fine lines. Widely used in anti-aging formulations, it’s valued for its safety profile and non-invasive mechanism of action.

Chemical Makeup

  • Molecular Formula: C₃₄H₆₀N₁₄O₁₂S

  • Molecular Weight: 888.99 g/mol

  • Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂

  • CAS Number: 616204-22-9

  • Other Names: Acetyl hexapeptide-3; Argireline

Research & Clinical Studies

Anti-Wrinkle Efficacy

  • Blanes-Mira et al. (2002): In vitro assays showed significant inhibition of SNARE-mediated vesicle fusion, indicating potential for reduced muscle contraction and wrinkle depth.<sup>1</sup>

  • Randomized Placebo-Controlled Trial (2013): Topical application in human subjects over 8 weeks reduced forehead wrinkle depth by up to 30% with no reported adverse effects.<sup>2</sup>

Mechanistic Insights

  • Autophagy & Collagen Synthesis: Emerging studies suggest that Argireline may also upregulate collagen III expression, improving skin elasticity over prolonged use.<sup>3</sup>

Recommended Usage

  • Typical Concentration: 0.001 – 2% in serums, creams, or lotions

  • Formulation Types: Best incorporated into water-based vehicles; compatible with pH 3–8

  • Solubility: Readily soluble in water; gentle warming may aid dissolution

Packaging & Storage

  • Packaging: 10 mg vial, amber glass

  • Shelf Life: Up to 2 years unopened

  • Storage Conditions: Store at 2–8 °C, protect from moisture and light

All products are sold for laboratory, research, or analytical purposes only. Not for human consumption.

References

  1. Blanes-Mira C. “A synthetic hexapeptide (Argireline) with antiwrinkle activity.” Int J Cosmet Sci. 2002 Oct.

  2. “The anti-wrinkle efficacy of acetyl hexapeptide-8: a randomized, placebo-controlled study.” Dermatol Res Pract. 2013 Apr.

  3. Smith et al. “Argireline’s role in collagen III upregulation.” J Cosmet Dermatol. 2020 Aug.

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FAQ

Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.

Yes. Reverse Peptides offers 99% purity, third-party tested, and USA-made peptides. Our products are backed by quality assurance and a loyal base of researchers

Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.

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No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.