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Description PT21 is a synthetic, 21-amino-acid peptide designed to mimic proline-rich motifs found in intracellular signaling proteins. By engaging SH3 domains and adaptor proteins, PT21 is widely used in research to dissect protein–protein interactions, receptor internalization pathways, and downstream kinase activation. Its optimized sequence enhances solubility and cell-permeability for robust in vitro and ex vivo assays….
Description PTD-DBM is a synthetic, cell-penetrating peptide engineered to interfere with the interaction between CXXC5 and Dishevelled (Dvl), a negative regulator of the Wnt/β-catenin pathway. By blocking this protein–protein interaction, PTD-DBM re-activates Wnt signaling in skin and follicular cells — driving processes associated with hair-follicle activation, wound-induced follicle neogenesis, dermal regeneration, and extracellular matrix remodeling. In…
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