ARA 290 (16mg)

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ARA-290 is an 11-amino acid linear peptide that functions as an agonist for the innate repair receptor (IRR). The IRR is a complex formed by the erythropoietin receptor and the beta-common (CD131) receptor, which together activate pathways that mediate anti-inflammatory responses and tissue repair. Research suggests that following peripheral nerve injury, the IRR is upregulated in the spinal cord and helps modulate the neurogenic inflammatory response.

What is Neuropathic Pain? What Are the Causes?

Neuropathic pain arises from damage or disease affecting the nervous system. It can be associated with various conditions, such as metabolic disorders, infectious diseases impacting small sensory nerve fibers (e.g., sarcoidosis), or central nervous system disorders like multiple sclerosis.

Symptoms of Neuropathic Pain

  • Allodynia: Increased sensitivity to non-painful stimuli

  • Tingling and Numbness

  • Spontaneous Pain: Pain occurring without a specific trigger

  • Difficulty Sleeping or Resting

  • Emotional Issues: Linked to chronic pain, such as anxiety, depression, and social isolation

Common Diseases That Can Cause Neuropathic Pain

  • Diabetes

  • Stroke

  • Multiple Sclerosis

  • Multiple Myeloma

Targeting the Innate Repair Receptor to Treat Neuropathy

Preclinical studies have shown that ARA-290 is effective in treating neuropathy without adverse effects. The peptide has been shown to transform a pro-inflammatory, tissue-damaging environment into one that supports healing and repair.

Potential Benefits of ARA-290

  • Pain Reduction

DISCLAIMER: FOR EXPERIMENTAL USE ONLY, NOT FOR PERSONAL USE