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KPV 10mg
$77.00
Description
KPV is a bioactive tripeptide fragment derived from the C-terminal sequence of alpha–melanocyte–stimulating hormone (α-MSH). It demonstrates potent anti-inflammatory and immunomodulatory effects by binding to melanocortin receptors and reducing pro-inflammatory cytokine release in various cell models.
Sequence
- Amino Acid Sequence: Lys–Pro–Val
- Other Names: α-MSH (11–13); Lys-Pro-Val Peptide
Research & Applications
- Anti-Inflammatory Activity: Reduces TNF-α, IL-1β, and IL-6 secretion in LPS-stimulated macrophages, supporting studies in inflammatory bowel disease and skin inflammation.
- Wound Healing: Promotes keratinocyte migration and accelerates wound closure in vitro, making it a tool for epithelial repair assays.
- Immune Modulation: Modulates dendritic cell maturation and T-cell activation, useful in autoimmune and transplant research.
Recommended Usage
- In Vitro: 1 – 50 µM in culture media for inflammation assays.
- Solubility: Soluble in sterile water or PBS; gentle warming (~37 °C) may aid dissolution.
- Compatibility: Compatible with serum-free and low-serum formulations.
Packaging & Storage
- Packaging: 10 mg amber glass vial with desiccant.
- Shelf Life: Up to 12 months unopened.
- Storage Conditions: Store at −20 °C; protect from moisture and light; avoid repeated freeze–thaw cycles.
All products are sold strictly for laboratory and analytical research use only. Not for human or veterinary consumption.
References
- MedChemExpress. KPV Tripeptide (Catalog No. HY-P0208), 10 mg. https://www.medchemexpress.com/hy-p0208.html
- Peptide Sciences. KPV (10 mg). https://www.peptidesciences.com/products/lyz-pro-val-kpv-tripeptide
- Cui, X. et al. “KPV peptide attenuates inflammatory responses in LPS-stimulated RAW264.7 macrophages.” Inflammation Research. 2019;68:863–872. https://pubmed.ncbi.nlm.nih.gov/31460471/
- Brzoska, T. et al. “KPV accelerates wound healing in human HaCaT keratinocytes.” Journal of Peptide Science. 2013;19(4):255–261. https://pubmed.ncbi.nlm.nih.gov/23652735/
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FAQ
1. What are research peptides?
Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.
2. Is Reverse Peptides a trusted source for buying peptides online?
Yes. Reverse Peptides offers 99% purity, third-party tested, and USA-made peptides. Our products are backed by quality assurance and a loyal base of researchers
3. How do I store research peptides after receiving them?
Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.
4. What payment methods do you accept?
We accept major credit/debit cards and secure online payment options. All transactions are encrypted and secure.
5. Is a prescription required to purchase peptides from Reverse Peptides?
No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.
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