Description
Humanin is a small peptide encoded within mitochondrial 16S rRNA, renowned for its potent neuroprotective and cytoprotective effects. It defends cells against oxidative stress, apoptosis, and metabolic insults, making it a valuable tool in research on neurodegenerative diseases (Alzheimer’s, Parkinson’s), cardiovascular protection, and cellular stress responses.
Sequence & Composition
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Amino Acid Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Lys-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
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Molecular Weight: ~2,687 Da
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Appearance: White to off-white lyophilized powder
Research & Applications
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Neuroprotection & Cytoprotection: Prevents neuronal and glial cell death under amyloid-β, oxidative stress, and serum-starvation conditions pmc.ncbi.nlm.nih.goven.wikipedia.org
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Cardiovascular Support: In rodent models, reduces myocardial apoptosis, limits infarct size, and preserves cardiac function post-ischemia pmc.ncbi.nlm.nih.gov
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Metabolic Regulation: Modulates insulin sensitivity and protects against atherosclerotic plaque formation via anti-inflammatory pathways en.wikipedia.org
Recommended Usage
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In Vitro: 0.1–10 µM in cell culture or assay buffer
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In Vivo (Rodent Studies): 0.5–2 mg/kg via intraperitoneal or intravenous injection, once daily or per protocol
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Solubility: Dissolve in sterile water or PBS; gentle warming (~37 °C) may aid dissolution
Packaging & Storage
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Packaging: 5 mg amber glass vial with desiccant pack
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Shelf Life: Up to 12 months unopened
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Storage Conditions: Store at 2–8 °C; protect from light and moisture; avoid repeated freeze–thaw cycles
For laboratory research use only. Not for human or veterinary consumption.
References
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Limitless Life Nootropics: Humanin 5 mg product overview limitlesslifenootropics.com
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Frontiers in Aging Neuroscience: “Mitochondrial-Derived Peptide Humanin in Aging” frontiersin.org
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ScienceDirect Topics: Humanin neuroprotective overview sciencedirect.com
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Wikipedia: Humanin research summary en.wikipedia.org
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FAQ
1. What are research peptides?
Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.
2. Is Reverse Peptides a trusted source for buying peptides online?
Yes. Reverse Peptides offers 99% purity, third-party tested, and USA-made peptides. Our products are backed by quality assurance and a loyal base of researchers
3. How do I store research peptides after receiving them?
Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.
4. What payment methods do you accept?
We accept major credit/debit cards and secure online payment options. All transactions are encrypted and secure.
5. Is a prescription required to purchase peptides from Reverse Peptides?
No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.
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