Humanin 5mg

Description

Humanin is a small peptide encoded within mitochondrial 16S rRNA, renowned for its potent neuroprotective and cytoprotective effects. It defends cells against oxidative stress, apoptosis, and metabolic insults, making it a valuable tool in research on neurodegenerative diseases (Alzheimer’s, Parkinson’s), cardiovascular protection, and cellular stress responses.

Sequence & Composition

• Amino Acid Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Lys-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala

• Molecular Weight: ~2,687 Da

• Appearance: White to off-white lyophilized powder

Research & Applications

• Neuroprotection & Cytoprotection: Prevents neuronal and glial cell death under amyloid-β, oxidative stress, and serum-starvation conditions pmc.ncbi.nlm.nih.goven.wikipedia.org

• Cardiovascular Support: In rodent models, reduces myocardial apoptosis, limits infarct size, and preserves cardiac function post-ischemia pmc.ncbi.nlm.nih.gov

• Metabolic Regulation: Modulates insulin sensitivity and protects against atherosclerotic plaque formation via anti-inflammatory pathways en.wikipedia.org

Recommended Usage

• In Vitro: 0.1–10 µM in cell culture or assay buffer

• In Vivo (Rodent Studies): 0.5–2 mg/kg via intraperitoneal or intravenous injection, once daily or per protocol

• Solubility: Dissolve in sterile water or PBS; gentle warming (~37 °C) may aid dissolution

Packaging & Storage

• Packaging: 5 mg amber glass vial with desiccant pack

• Shelf Life: Up to 12 months unopened

• Storage Conditions: Store at 2–8 °C; protect from light and moisture; avoid repeated freeze–thaw cycles

For laboratory research use only. Not for human or veterinary consumption.

References

1. Limitless Life Nootropics: Humanin 5 mg product overview limitlesslifenootropics.com

2. Frontiers in Aging Neuroscience: “Mitochondrial-Derived Peptide Humanin in Aging” frontiersin.org

3. ScienceDirect Topics: Humanin neuroprotective overview sciencedirect.com

4. Wikipedia: Humanin research summary en.wikipedia.org