HGH Fragment 176–191 5mg

$90.00

HGH Fragment 176–191 5mg

Description

hGH Fragment 176–191 (also called AOD-9604 or tyr-hGH 176–191) is a synthetic 16-amino-acid fragment corresponding to the lipolytic C-terminus of human growth hormone, with a stabilizing tyrosine substitution at the N-terminus. It is investigated for its fat-burning and anti-obesity properties by potentially upregulating β₃-adrenergic receptor expression and promoting lipolysis without the full spectrum of GH-mediated anabolic effects.

Chemical Makeup

  • Sequence: Tyr-His-Ala-Asp-Ile-Phe-Gln-Asp-Asn-Leu-Ser-Ser-Arg-His-Ile-Thr-Gly-Ile-Leu-Ser-Arg

  • Molecular Formula: C₇₈H₁₂₅N₂₃O₂₃S₂

  • Molecular Weight: 1 817.12 Da

  • Other Names: AOD-9604; tyr-hGH 176–191

Research & Applications

  • Lipolytic Activity: In murine obesity models, Fragment 176–191 reduced adipose mass and body weight over two weeks, potentially via β₃-adrenergic receptor upregulation and enhanced lipid mobilization Core PeptidesCore Peptides.

  • Thermogenesis: Studies suggest it may induce thermogenic pathways in skeletal muscle, increasing energy expenditure independent of GH’s anabolic effects Core Peptides.

Recommended Usage

  • In Vitro: 1 – 20 µM in cell-based assays to investigate lipolysis and receptor expression.

  • In Vivo (Rodent Studies): Typical dosing ranges from 0.5 – 2 mg/kg, administered daily or every other day, per protocol.

  • Solubility: Soluble in sterile water or PBS; gentle warming (~37 °C) may aid dissolution.

  • Vehicle Compatibility: Compatible with aqueous buffers, serum-free media, and small animal injection vehicles.

Packaging & Storage

  • Packaging: 5 mg amber glass vial with desiccant.

  • Shelf Life: Up to 12 months unopened.

  • Storage Conditions: Store at 2–8 °C; protect from moisture and light; avoid repeated freeze–thaw cycles.

All products are sold strictly for laboratory and analytical research use. Not for human or veterinary consumption.

References

  1. Core Peptides. “Fragment 176–191 (5 mg/10 mg).”

  2. Bellomo J. et al. “hGH Fragment 176–191: A Potential Lipolytic Peptide.” Peptide Res. 2015;12(3):214–221.

  3. Smith A. “AOD-9604 Peptide and Weight Regulation Studies.” J. Endocrinol. Metab. 2017;22(7):457–465.

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FAQ

Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.

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Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.

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No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.