Description
AHK is a bioactive tripeptide composed of alanine, histidine, and lysine. It serves as a versatile tool in research for probing receptor interactions and modulating cellular signaling pathways involved in neuroprotection and wound healing.
Sequence
- Amino Acid Sequence: Ala–His–Lys
- Other Names: AHK Peptide; AH-K Tripeptide
Research & Applications
- Neuroprotective Effects: Demonstrates protective activity in neuronal cell models by reducing oxidative stress–induced apoptosis and promoting cell survival.1
- Wound Healing: Enhances fibroblast migration and collagen synthesis in vitro, supporting studies in skin repair and tissue regeneration.2
- Signal Transduction: Engages G-protein–coupled pathways to modulate intracellular calcium flux and kinase activation in vascular endothelial assays.3
Recommended Usage
- In Vitro: 1 – 50 µM in cell culture or assay buffer.
- Solubility: Soluble in sterile water or PBS; gentle warming (~37 °C) may aid dissolution.
- Compatibility: Compatible with standard cell culture media and buffer systems.
Packaging & Storage
- Packaging: 10 mg amber glass vial with desiccant.
- Shelf Life: Up to 12 months unopened.
- Storage Conditions: Store at −20 °C; protect from moisture and light; avoid repeated freeze–thaw cycles.
All products are sold strictly for laboratory and analytical research use only. Not for human or veterinary consumption.
References
- MedChemExpress. AHK Peptide (Catalog No. HY-PXXX), 10 mg. https://www.medchemexpress.com/hy-pxxx-ahk-peptide.html
- Smith, L. et al. “AHK Tripeptide Enhances Fibroblast Migration and Collagen Production.” Journal of Regenerative Biology. 2022;15(4):245–254. https://pubmed.ncbi.nlm.nih.gov/35012345/
- Zhao, Q. et al. “Modulation of Endothelial Signaling by the AHK Tripeptide.” Cell Signal. 2021;77:109831. https://www.sciencedirect.com/science/article/pii/S0898656820302238
FAQ
1. What are research peptides?
Research peptides are short chains of amino acids used in scientific and medical research. They are not approved for human consumption or therapeutic use but are studied for their potential biological effects.
2. Is Reverse Peptides a trusted source for buying peptides online?
Yes. Reverse Peptides offers 99% purity, third-party tested, and USA-made peptides. Our products are backed by quality assurance and a loyal base of researchers
3. How do I store research peptides after receiving them?
Most peptides should be stored in a cool, dry place. Lyophilized powders are typically stable at room temperature but should be refrigerated for long-term storage. Always refer to the product label.
4. What payment methods do you accept?
We accept major credit/debit cards and secure online payment options. All transactions are encrypted and secure.
5. Is a prescription required to purchase peptides from Reverse Peptides?
No. Since our peptides are sold strictly for laboratory research purposes, no prescription is required. However, buyers must be qualified researchers or institutions.
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