Selank 10mg

Description

Selank is a synthetic heptapeptide analogue of the endogenous immunoregulatory peptide tuftsin, engineered for enhanced metabolic stability. It modulates cytokine balance (including IL-6), influences monoamine neurotransmitter levels, and upregulates BDNF, resulting in rapid anxiolytic and cognitive-enhancing effects. Widely used in research on anxiety disorders, memory, neuroprotection, and stress resilience, Selank offers a non-sedating alternative to traditional anxiolytics.

Sequence & Composition

• Amino Acid Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro

• Molecular Formula: C₃₃H₅₇N₁₁O₉

• Molecular Weight: 751.9 Da

• CAS Number: 129954-34-3

Research & Applications

• Anxiolytic Activity: Demonstrates significant reduction of anxiety-like behavior in preclinical and clinical studies.

• Cognitive Enhancement: Improves learning and memory performance via upregulation of BDNF and modulation of GABAergic signaling.

• Immunomodulation: Balances Th1/Th2 cytokine profiles and reduces enkephalinase activity, supporting neuroimmune health.

• Neuroprotection: Protects against stress-induced neuronal damage and supports recovery in ischemia and trauma models.

Recommended Usage

• In Vitro: 0.1–10 µM in cell culture or assay buffer.

• In Vivo (Rodent Studies): 50–200 µg/kg via intraperitoneal or intravenous administration, once daily or per protocol.

• Solubility: Dissolve in sterile water or PBS; gentle warming (~37 °C) may aid dissolution.

Packaging & Storage

• Packaging: 10 mg amber glass vial with desiccant pack.

• Shelf Life: Up to 12 months unopened.

• Storage Conditions: Store at 2–8 °C; protect from light and moisture; avoid repeated freeze–thaw cycles.

For laboratory research use only. Not for human or veterinary consumption.

References

1. Peptide Sciences: “Selank (10 mg) | 99% Purity” peptidesciences.com

2. Certificate of Analysis: Selank peptide, purity ≥ 99% by HPLC novoprolabs.com

3. Wikipedia: “Selank” en.wikipedia.org